All About Mitragynine- A Mind-Altering Alkaloid

Last Updated on August 29, 2023 by

Having consumed Mitragynine:

A Mind-Altering Alkaloid, it is easy to see how people become addicted. Discover all about this mind-altering alkaloid and the medical benefits of this natural remedy in this blog post.

Mitragynine or kratom from Slo Kratom is a popular plant with several different uses. Many people use it to treat depression, anxiety, and withdrawal symptoms from opiates. This plant has many other benefits, making it a good idea to learn more about this fantastic herb.

It is a plant with its roots in Thailand, the leaves used to make tea. Mitragynine is present in the highest concentration in these leaves, and it is this alkaloid that Kratom users cite as having a variety of medicinal benefits.

Have you ever heard of the benefits of kratom? If not, then you are in for a surprise. It has medical benefits and can help people manage pain and mood disorders. Find out all about this alkaloid in this article!

What Is Mitragynine Or Kratom?

Kratom is the plant’s name: Mitragyna speciosa, used for centuries in Southeast Asia, primarily Indonesia and Malaysia, as an analgesic and stimulant. For centuries, the plant’s leaves have been used in Thailand and Myanmar as an opiate substitute.

It has a variety of effects, including euphoria and pain relief. It is currently used in Western countries to remedy opioid addiction and social anxiety, depression, chronic fatigue syndrome, and fibromyalgia.

It contains a substance called mitragynine (or 7-hydroxy mitragynine), responsible for the effects you feel when you consume it. Mitragynine works as an opioid receptor agonist, meaning that it binds to receptors in your brain and stimulates specific cells in your nervous system.

The leaves are brewed into a tea, chewed for its numbing effect on the mouth and gums, smoked. It stimulates or makes capsules or powder for snorting or cooking.

And that makes it no different from any other drug except that there is no risk of addiction. Slo kratom can be bought online at many websites and has become popular as a dietary supplement because it is legal to sell and use in most places where drugs are illegal.

Medical Benefits Of Mind-Altering Alkaloid (Kratom)

Kratom or mitragynine is a robust and well-tested medicinal used throughout the world. It got first utilized by the natives of Southeast Asia to treat pain but then became famous to Westerners looking for a “natural” alternative to prescription medications. The herbal supplement has helped treat chronic pain, anxiety, depression, and insomnia.

Let’s check out in detail the medical benefits of consuming this herb:

Treats Anxiety/Panic Attacks

Kratom is helpful for many people suffering from anxiety and panic attacks to help them cope with conditions that may have contributed to the onset of these disorders. It’s a psychoactive drug and an alkaloid. It’s also associated with various pharmacological effects, including pain relief, euphoria, and anti-anxiety effects. The valuable alkaloids in kratom include mitragynine and 7-hydroxy mitragynine. They are the only ones that have gotten well characterized. Mitragynine is the main active compound found in kratom (20-30% dry weight). It is an all-in-one supplement to help those who suffer from anxiety and panic attacks.

Helps To Treat Chronic Pain

Helps To Treat Chronic Pain

The leaves of this kratom plant are usually ground into a powder or tea and crushed into capsules that can get swallowed. These compounds have shown promising results as they have shown an ability to treat chronic pain, especially the type of pain that comes from nerve damage. A natural component of kratom leaves, mitragynine, relieves pain by acting on opioid receptors in the brain. According to some studies, mitragynine also works on other receptors such as apoptosis-inhibiting enzymes, which may explain why it could help treat chronic pain. It is also famous for helping with depression, anxiety, and other psychological issues.

Manages Opiate Withdrawal Symptoms

Opiate withdrawal, delirium tremens (DTs), and mental illness are the most common causes of death when an opioid user tries to quit. A typical opiate user goes through withdrawal symptoms upon cessation of their drug intake. In contrast, Kratom users tend to experience less severe withdrawals and, in some cases, no withdrawal at all. The kratom plant is also a safe alternative for people who want to discontinue painkillers but are trying to avoid the adverse side effects associated with these drugs. In other words, when mitragynine binds to one μ-opioid receptor site, it produces results similar to those produced by opiates like morphine.

Contains Sedative Properties

Kratom is an herb that has sedative and analgesic properties. It is available in most parts of the world and getting used as a stimulant or a sedative. Kratom can be ingested, smoked, or brewed in tea. The main active substance present in kratom is mitragynine, which has psychoactive properties. Mitragynine binds to mu-opioid receptors and reduces pain perception, moods, and anxiety levels by activating the brain’s reward system. Apart from this, mitragynine also acts as a mild sleep aid, with studies showing that it induces relaxation similar to that caused by benzodiazepines.

Acts As An Anti-Inflammatory

Mitragynine acts as an anti-inflammatory. It is due to its alkaloids, mitragynine, and 7-hydroxy mitragynine. It works by inhibiting the cyclooxygenase enzymes that produce prostaglandin E2 (PGE2) from arachidonic acid. These are similar to the chemicals produced by your own body that cause inflammation and pain. The inhibition of these enzymes makes arachidonic acid less available, so they can’t make PGE2. When they aren’t making PGE2 well, PGE2 doesn’t accumulate in the joint, and the inflammation gets reduced or stopped altogether. Hence, it possesses antioxidant, antimicrobial, anti-inflammatory, and anti-diabetic properties.


Mitragynine is a unique alkaloid found in the leaves and extracts of Mitragyna speciosa, also known as kratom, an evergreen tree native to Southeast Asia in the coffee family.

For centuries, people have used this plant as an herbal remedy for pain, anxiety, and exhaustion by native people in Thailand, where its native home is present. It helps to relieve pain, boost energy, and promote well-being. The leaves can be chewed or brewed into tea.

Most people are using it as a remedy for different illnesses, and it also has beneficial effects on mood. When taken as an intoxicant, mitragynine can cause a dose-dependent state of euphoria and distorted reality.And before consuming it also take Kratom strain guide.

But just because it’s legal in the US doesn’t mean you can buy it in stores. You’ll have to get your hands on some locally and know the right way to use it properly.